![]() ![]() Mothers with HBV DNA higher than 8 log 10 copies/mL had an incidence range from 7.6% to 33.3% and pooled incidence of 14.445% (95% CI, 8.317-20.572).įinally, the researchers found that linear dose-response showed significant and evolutionary risk of mother-to-child transmission of HBV along increased maternal viral load (OR = 1.393 95% CI, 1.218-1.594) for each log 10 copy/mL increase. Among mothers with HBV DNA less than 6 log 10 copies/mL, the researchers found that incidence ranged from 0% to 6.7% and pooled incidence was 2.754% (95% CI, 1.198-4.31). The researchers conducted a subgroup analysis of mother-to-child transmission incidence by HBV DNA level. 00001), although there was evidence of publication bias. ![]() The researchers found significant heterogeneity between studies ( P <. Mothers positive for HBV DNA had a significantly higher risk for transmission to child (OR = 9.895 95% CI, 5.333-19.359). Mean mother-to-child transmission incidence in patients positive for HBV DNA was 13.1% (range, 3.1%-81.5%), compared with 4.2% (range, 0%-39.4%) among mothers negative for HBV DNA. Mother-to-child transmission incidence ranged from 1.54% to 45.5%. Most studies were published within the previous 10 years and were conducted in China. “HBV infection acquired via mother-to-child transmission (MTCT) is typically considered to be one of the major causes of chronic infection.”Ĭhen and colleagues identified 21 studies with 10,142 mother-child pairs for evaluation. According to WHO estimates, 240 million people are chronically infected with hepatitis B,” Hong-Lin Chen, MD, from the Nantong University, China, and colleagues wrote. “Hepatitis B virus (HBV) infection is a major global health problem. If you continue to have this issue please contact to HealioĪ systematic review and meta-analysis revealed that maternal viral load among mothers with hepatitis B was a significant risk factor for mother-to-child transmission, and was dose-dependent with HBV transmission incidence. All adults 18 years and older should get screened at least once in their lifetime.We were unable to process your request. All adults aged 18-59 should receive the vaccine and any adult who requests it may get the vaccine. The best way to prevent hepatitis B is to get vaccinated. By contrast, almost all children 6 years and older and adults infected with the hepatitis B virus recover completely and do not develop chronic infection. About one in three children who get infected before age 6 will develop chronic hepatitis B. ![]() The risk goes down as a child gets older. About 9 in 10 infants who become infected go on to develop life-long, chronic infection. The younger a person is when infected with the hepatitis B virus, the greater the chance of developing chronic infection. Age plays a role in whether hepatitis B will become chronic. For others, it can become a long-term, chronic infection that can lead to serious, even life-threatening health issues like liver disease or liver cancer. For many people, hepatitis B is a short-term illness. Not all people newly infected with HBV have symptoms, but for those that do, symptoms can include fatigue, poor appetite, stomach pain, nausea, and jaundice. This can happen through sexual contact sharing needles, syringes, or other drug-injection equipment or during pregnancy or delivery. Hepatitis B is spread when blood, semen, or other body fluids from a person infected with the virus enters the body of someone who is not infected. Hepatitis B is a vaccine-preventable liver infection caused by the hepatitis B virus (HBV). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |